J Clin Endocrinol Metab. 1987 Jul;65(1):188-93.
The effects of a 5 alpha-reductase inhibitor and antiandrogen, 4-MA, on the development of baldness in the stumptail macaque.
Rittmaster RS, et al
We used a model of male-pattern baldness to test the efficacy of a topically applied 5 alpha-reductase inhibitor and antiandrogen (4-MA) in the prevention of baldness. Six periadolescent stumptail macaques were given daily topical applications of either 4-MA in dimethylsulfoxide or dimethylsulfoxide alone for 27 months. The three control monkeys developed varying degrees of baldness, while the three 4-MA-treated monkeys retained their juvenile pattern of hair regrowth. snip… We conclude that topical 4-MA can prevent the development of baldness in the stumptail macaque, a primate model of androgen-dependent baldness.