Acta Derm Venereol. 1988;68(2):116-22
LPatche tests
Immunohistochemistry of lymphocytes and Langerhans’ cells in long-lasting allergic patch tests.
Kanerva L, et al
A long-lasting allergic patch test is a “normal” allergic patch test that remains positive for weeks or months. An immunohistochemical study of immunocompetent cells in the skin in this rare type of patch tests was performed. snip.. hair loss..An inflammatory reaction of hair follicles with moderate numbers of T6+ cells in the peribulbar infiltrate was observed indicating that hair follicles might act as shunt pathways for allergens. A defect in down regulation of the contact hypersensitivity reaction and/or a constant antigen stimulation could be responsible for the long-lasting allergic patch tests.